If you’re searching for the ultimate comfort food that’s as easy as it is irresistible, the Chicken Bubble Biscuit Bake Casserole is about to become your new weeknight hero. Juicy bites of chicken, creamy sauce, and melt-in-your-mouth biscuits all bake together until golden and bubbling, filling your kitchen with aromas that practically guarantee the family will come running. Whether you’re feeding a crowd or just need something quick and cozy, this dish never disappoints. The Chicken Bubble Biscuit Bake Casserole is a true shortcut to hearty, homey deliciousness.

Ingredients You’ll Need
Nothing fancy here, just pantry staples that shine bright once mixed together! Every ingredient in Chicken Bubble Biscuit Bake Casserole has its role—creaminess, richness, savory flavor, or a kick of cheddar. Let’s break down why each part matters.
- 2 cups cooked shredded chicken: Using rotisserie chicken or leftovers keeps things speedy and juicy.
- 1 (10.5 oz) can cream of chicken soup: Brings luscious creaminess and savory depth to the dish.
- 1/2 cup sour cream: Adds a tangy richness that brightens up every bite.
- 1/2 cup shredded cheddar cheese: Melts into gooey perfection and gives a savory kick.
- 1/2 teaspoon garlic powder: For a subtle, tasty hint of garlic in every forkful.
- 1/2 teaspoon onion powder: Boosts flavor with zero chopping required.
- 1/4 teaspoon black pepper: Lends a mild warmth and balances the flavors.
- 1 (16.3 oz) can refrigerated biscuits, cut into quarters: The biscuits “bubble up” bake into delicious, fluffy pillows.
- 1 tablespoon melted butter: Brushed on top for irresistible golden color and flavor.
- 1 teaspoon dried parsley (optional): Optional, but perfect for an extra pop of green at the end.
How to Make Chicken Bubble Biscuit Bake Casserole
Step 1: Prep the Oven and Dish
Let’s get started by preheating your oven to 350°F (175°C). Give your trusty 9×13-inch baking dish a good greasing—this ensures nothing sticks and every serving comes out picture perfect. Taking a quick moment for prep here makes the rest of the Chicken Bubble Biscuit Bake Casserole process a breeze.
Step 2: Mix the Creamy Filling
Grab a large bowl and combine the shredded chicken, cream of chicken soup, sour cream, cheddar cheese, garlic powder, onion powder, and black pepper. Mix until everything is evenly blended. This is the heart of your Chicken Bubble Biscuit Bake Casserole—the spot where all those creamy, cheesy flavors come together.
Step 3: Fold in the Biscuits
Next, gently fold your biscuit pieces into the creamy mixture. Make sure each nugget is well coated but be gentle—overmixing can squash those beautiful biscuit layers. These “bubbles” will bake up to fluffy perfection!
Step 4: Bake to Bubbling Perfection
Spoon everything evenly into your prepared baking dish. Brush the top with melted butter and, if you want a touch of color, sprinkle on that dried parsley. Pop it in the oven for 30–35 minutes until it’s golden, bubbling, and smells downright heavenly. Give it a rest for 5–10 minutes before digging in, which makes serving even easier.
How to Serve Chicken Bubble Biscuit Bake Casserole

Garnishes
Take things up a notch by adding a fresh sprinkle of chopped parsley, sliced green onions, or a little extra cheese on top right before serving. These easy garnishes amp up both flavor and eye appeal, making the Chicken Bubble Biscuit Bake Casserole look every bit as special as it tastes.
Side Dishes
Pair your casserole with a simple green salad, crisp steamed veggies, or even some roasted broccoli—the creamy, rich flavors complement lighter sides so well. For hungry eaters, a spoonful of applesauce or classic coleslaw is always a hit next to Chicken Bubble Biscuit Bake Casserole.
Creative Ways to Present
Scoop individual servings into small bowls or ramekins for a cozy, personalized touch. If you’re hosting brunch, serve with a fried egg on top for a decadent spin. Leftovers? Reheat and stuff into a sandwich for the ultimate comfort food lunch!
Make Ahead and Storage
Storing Leftovers
Once cooled, transfer any leftover Chicken Bubble Biscuit Bake Casserole to an airtight container and refrigerate. It will keep well for up to 3 days, and the flavors somehow get even better the next day, making it a fabulous grab-and-go lunch!
Freezing
You can absolutely freeze Chicken Bubble Biscuit Bake Casserole, just let it cool completely first. Wrap tightly in foil or store in freezer-safe containers. It will keep for up to 2 months. When a craving hits, you’re already halfway to an easy dinner.
Reheating
To reheat, pop the casserole in a 350°F oven (covered with foil to keep it moist) until warmed through, about 20 minutes. Individual portions can also be microwaved—just be sure to cover them so the biscuits don’t dry out and the filling stays creamy.
FAQs
Can I use leftover turkey instead of chicken?
Absolutely! Substitute cooked shredded turkey for the chicken in your Chicken Bubble Biscuit Bake Casserole with no changes to the recipe. It’s especially delicious after the holidays!
Is it possible to make this dish ahead of time?
Yes, you can assemble the casserole (everything except baking) up to a day in advance. Cover and refrigerate, then just pop it in the oven when you’re ready. You may need to add an extra 5–10 minutes to the baking time if it’s cold from the fridge.
What type Main Course
Both regular and flaky layer refrigerated biscuits work beautifully in Chicken Bubble Biscuit Bake Casserole. The flaky kind rise into especially pillowy bubbles, but use whichever you prefer or have on hand.
Can I add vegetables to the casserole?
Totally! Feel free to stir in a cup of cooked vegetables like peas, diced carrots, broccoli, or even sautéed mushrooms for extra color and nutrition. Just be sure they’re cooked and drained before mixing in.
How do I make Chicken Bubble Biscuit Bake Casserole extra cheesy?
If you’re a cheese lover, simply double the cheddar or sprinkle some on top before baking. The result is an extra decadent, gooey-topped casserole that’ll make any cheese fan smile.
Final Thoughts
When you need a cozy, crowd-pleasing dinner that comes together in a snap, you simply can’t go wrong with Chicken Bubble Biscuit Bake Casserole. It’s creamy, satisfying, and as fun to make as it is to eat. Give it a try—you’ll soon see why it’s a staple in so many kitchens!
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Chicken Bubble Biscuit Bake Casserole Recipe
- Total Time: 45 minutes
- Yield: 6 servings 1x
- Diet: Non-Vegetarian
Description
This Chicken Bubble Biscuit Bake Casserole is a comforting and flavorful dish that combines tender shredded chicken with a creamy sauce, topped with buttery, flaky biscuits. It’s a simple yet satisfying meal that the whole family will love.
Ingredients
Chicken Mixture:
- 2 cups cooked shredded chicken
- 1 (10.5 oz) can cream of chicken soup
- 1/2 cup sour cream
- 1/2 cup shredded cheddar cheese
- 1/2 teaspoon garlic powder
- 1/2 teaspoon onion powder
- 1/4 teaspoon black pepper
Biscuit Topping:
- 1 (16.3 oz) can refrigerated biscuits (8-count, regular or flaky layers), cut into quarters
- 1 tablespoon melted butter
- 1 teaspoon dried parsley (optional)
Instructions
- Preheat the oven: Preheat the oven to 350°F (175°C) and grease a 9×13-inch baking dish.
- Mix Chicken Mixture: In a large bowl, combine shredded chicken, cream of chicken soup, sour cream, cheddar cheese, garlic powder, onion powder, and black pepper.
- Add Biscuit Topping: Gently fold in the biscuit pieces until evenly coated. Transfer the mixture to the baking dish.
- Top and Bake: Brush the top with melted butter, sprinkle with dried parsley, and bake for 30–35 minutes until golden and bubbling.
- Serve: Let cool for 5–10 minutes before serving.
Notes
- For added flavor, stir in cooked bacon or steamed vegetables.
- You can use rotisserie chicken for convenience.
- Prep Time: 10 minutes
- Cook Time: 35 minutes
- Category: Main Course
- Method: Baking
- Cuisine: American
Nutrition
- Serving Size: 1 portion
- Calories: 390
- Sugar: 3g
- Sodium: 950mg
- Fat: 24g
- Saturated Fat: 10g
- Unsaturated Fat: 11g
- Trans Fat: 0g
- Carbohydrates: 24g
- Fiber: 1g
- Protein: 20g
- Cholesterol: 65mg