If you’re looking for a rich, creamy comfort dish that comes together easily, Chicken and Spinach Casserole with Cream Cheese is always a winner at my table! This classic bake combines juicy shredded chicken, fresh spinach, and a dreamy, cheesy sauce that will make everyone reach for seconds. It’s perfect for busy weeknights, cozy gatherings, or anytime you just need a soul-warming meal that tastes like a big hug. Plus, it’s naturally low-carb and gluten-free, making it a favorite among friends with different dietary needs. Trust me, after one bite, Chicken and Spinach Casserole with Cream Cheese will become a regular request in your house too.
Ingredients You’ll Need
Each ingredient for this Chicken and Spinach Casserole with Cream Cheese was handpicked to make sure you get both flavor and texture in every satisfying bite. Even the basics matter here, and every addition—from the cheeses to a touch of red pepper—adds its own magic to the final dish.
- Cooked shredded chicken breast: The juicy base to soak up all that creamy sauce; rotisserie chicken is fantastic for convenience.
- Fresh baby spinach: Adds vibrant color and a burst of nutrients plus it wilts perfectly for a luscious texture.
- Cream cheese (softened): The star ingredient, bringing the rich, tangy creaminess that ties everything together.
- Shredded mozzarella cheese: Melts to gooey perfection, helping form that irresistible cheesy top crust.
- Grated Parmesan cheese: Adds a nutty, salty finish to boost umami and give the topping its golden color.
- Sour cream: Rounds out the sauce and adds just the right amount of tanginess.
- Heavy cream: Makes the sauce extra silky and indulgent—don’t skip it for maximum creaminess.
- Garlic (minced): Brings subtle warmth and loads of flavor that spreads through every layer.
- Small onion (finely chopped): Gives aromatics and a gentle sweetness that balances the richness.
- Olive oil: Used for sautéing to deepen the taste of the onion and garlic.
- Dried Italian seasoning: A quick way to bring herbaceous notes—think oregano, basil, a hint of thyme.
- Salt: Essential for making every flavor pop.
- Black pepper: Adds a little zip to cut the creaminess.
- Crushed red pepper flakes (optional): Gives a gentle heat for those who like a kick—feel free to skip or increase to your preference!
How to Make Chicken and Spinach Casserole with Cream Cheese
Step 1: Prepare Your Oven and Pan
Set your oven to preheat at 375°F (190°C). Take a 9×13-inch baking dish and coat it lightly with cooking spray or a bit of olive oil—this helps prevent sticking and guarantees that golden, bubbly finish we all love.
Step 2: Sauté the Aromatics and Spinach
In a large skillet, warm your olive oil over medium heat. Toss in the finely chopped onion and let it cook until soft and translucent—about 3 minutes. Stir in the minced garlic and cook for just 1 minute more; you’ll smell how fragrant your kitchen becomes! Add the fresh baby spinach and sauté until it’s completely wilted, then remove the skillet from heat to let the mixture cool slightly.
Step 3: Mix Together the Creamy Base
Grab a big mixing bowl and combine the softened cream cheese, sour cream, and heavy cream. Beat them together until completely smooth and blended—this is what gives Chicken and Spinach Casserole with Cream Cheese its signature, melt-in-your-mouth texture.
Step 4: Combine Chicken, Spinach, and Seasonings
Add your shredded chicken to the bowl, along with the sautéed spinach mixture. Sprinkle in the Italian seasoning, salt, black pepper, and optional red pepper flakes. Stir until you have a luxuriously creamy filling, evenly mixed so every forkful gets some chicken, spinach, and that dreamy sauce.
Step 5: Assemble and Top Your Casserole
Spoon your mixture into the prepared baking dish, spreading it out to reach every edge. Generously scatter the shredded mozzarella and then the grated Parmesan all over the top. This double-cheese topping is key to a perfectly golden brown, bubbly finish on your Chicken and Spinach Casserole with Cream Cheese.
Step 6: Bake to Perfection
Slide the dish into your preheated oven and bake for 25 to 30 minutes. You’ll know it’s ready when the casserole is bubbling at the edges and the cheese has formed a lightly toasted, irresistible crust. Resist digging in right away—let it rest for a few minutes so it sets and cuts cleanly.
How to Serve Chicken and Spinach Casserole with Cream Cheese
Garnishes
Fresh garnishes always give casseroles a lovely pop of color and flavor. I love dusting the top with chopped fresh parsley or a sprinkle of extra red pepper flakes for a hint of heat. For maximum wow, a drizzle of olive oil or a few fresh basil leaves can also work wonders atop your Chicken and Spinach Casserole with Cream Cheese just before serving.
Side Dishes
This casserole is wonderfully filling all on its own, but pairing it with a light, crisp salad—think arugula, lemon, and shaved Parmesan—is delicious. Roasted veggies like broccoli or asparagus on the side add extra color and nutrients, while cauliflower rice or mashed cauliflower keep things low carb and complete the meal beautifully.
Creative Ways to Present
If you want to elevate your Chicken and Spinach Casserole with Cream Cheese for a special occasion, try baking and serving it in individual ramekins for personalized mini-casseroles. Or, you can portion it into lettuce cups for a fun, hand-held appetizer at a party. I’ve even piled leftovers into a toasted sandwich the next day—talk about comfort food magic!
Make Ahead and Storage
Storing Leftovers
If you’re lucky enough to have some casserole left, simply cover the baking dish tightly with foil or transfer to airtight containers. Store in the refrigerator, where it will stay fresh and delicious for up to 3 days. It’s just as creamy and tasty the next day, making lunch a breeze!
Freezing
Chicken and Spinach Casserole with Cream Cheese freezes beautifully. Cool the casserole completely, portion it into individual servings, and wrap well with plastic wrap before popping into freezer bags or containers. It’ll keep for up to 2 months—perfect for busy days when you need a comforting meal in a snap.
Reheating
To reheat, thaw overnight in the fridge if frozen, then bake covered at 350°F until warm throughout (about 20 minutes). If you’re reheating a single portion, the microwave works too—just don’t forget to cover and add a splash of cream to keep it creamy. Let it stand for a minute before enjoying so it settles nicely.
FAQs
Can I use rotisserie chicken instead of cooking chicken breast?
Absolutely! Rotisserie chicken makes things even easier and adds a ton of flavor. Just shred it well and you’re good to go—plus, it helps you get this casserole on the table even faster.
Can I substitute frozen spinach for fresh?
You can! Just be sure to thaw and squeeze out as much liquid as possible before mixing it in, so your Chicken and Spinach Casserole with Cream Cheese won’t be watery.
Is this recipe keto-friendly?
Yes, this casserole is naturally low in carbs and perfect for those following keto or low-carb diets. You get all the cheesy, creamy goodness without the need for breadcrumbs or flour.
What’s the best way to soften cream cheese quickly?
Cut the cream cheese into smaller cubes and let it sit at room temperature for 20 minutes. If you’re in a hurry, microwave it in short 10-second bursts until just soft but not hot.
Can I add other veggies to the casserole?
Definitely! Feel free to stir in sautéed mushrooms, chopped bell peppers, or even broccoli florets to customize your Chicken and Spinach Casserole with Cream Cheese to your liking.
Final Thoughts
You’ll find that Chicken and Spinach Casserole with Cream Cheese is comforting, filling, and packed with flavor—all with simple ingredients you probably already have in your kitchen. Whip it up for a crowd, a family meal, or a cozy dinner for two; every time, you’ll wish you made more. Give it a try and let this casserole earn its place as your new go-to favorite!
Print
Chicken and Spinach Casserole with Cream Cheese Recipe
- Total Time: 45 minutes
- Yield: 6 servings 1x
- Diet: Non-Vegetarian
Description
Indulge in this creamy and savory Chicken and Spinach Casserole with Cream Cheese that’s bursting with flavor. A low-carb delight that’s perfect for a satisfying family meal.
Ingredients
For the Casserole:
- 3 cups cooked shredded chicken breast
- 6 ounces fresh baby spinach
- 8 ounces cream cheese, softened
- 1 cup shredded mozzarella cheese
- 1/2 cup grated Parmesan cheese
- 1/2 cup sour cream
- 1/2 cup heavy cream
- 2 cloves garlic, minced
- 1 small onion, finely chopped
- 1 tablespoon olive oil
- 1 teaspoon dried Italian seasoning
- 1/2 teaspoon salt
- 1/4 teaspoon black pepper
- 1/4 teaspoon crushed red pepper flakes (optional)
Instructions
- Preheat Oven: Preheat oven to 375°F (190°C).
- Sauté Onion and Garlic: In a skillet, sauté onion in olive oil until translucent. Add garlic and cook for a minute.
- Add Spinach: Add spinach, sauté until wilted, then remove from heat.
- Mix Ingredients: In a bowl, combine cream cheese, sour cream, and heavy cream. Add chicken, spinach mixture, seasonings, and mix well.
- Bake: Transfer mixture to a baking dish, top with cheeses, and bake for 25-30 minutes until golden.
- Serve: Let it rest before serving.
Notes
- Enhance with crispy bacon bits before baking.
- Substitute kale for spinach if preferred.
- Prep Time: 15 minutes
- Cook Time: 30 minutes
- Category: Main Course
- Method: Baking
- Cuisine: American
Nutrition
- Serving Size: 1 portion
- Calories: 420
- Sugar: 2g
- Sodium: 520mg
- Fat: 32g
- Saturated Fat: 16g
- Unsaturated Fat: 14g
- Trans Fat: 0g
- Carbohydrates: 5g
- Fiber: 1g
- Protein: 32g
- Cholesterol: 120mg
